Heather Graham as Dr. Elizabeth Derby

Judah Lewis as Asa Waite

Bruce Davison as Ephraim Waite

Johnathon Schaech as Edward Derby

Barbara Crampton as Dr. Daniella Upton

Graham Skipper as Pathologist

Brett A. Newton as Professor Fisk

Chris L. McKenna as Crawley

J.D. Evermore as Detective Ledger

Giovannie Cruz as Officer Huxley

Ann Mahoney as Susan

Hunter Womack as Mace, Jr.

Jonah Ray Rodrigues as Dave the Orderly

Joe Lynch as Ray the Orderly

Drake Malone as Resident

Kim Barnard as Nurse