Jet Li as Rogue

Jason Statham as Special Agent Jack Crawford

John Lone as Li Chang

Ryo Ishibashi as Shiro Yanagawa

Devon Aoki as Kira Yanagawa

Mark Cheng Ho-Nam as Wu Ti

Luis Guzmán as Benny

Saul Rubinek as Dr. Sherman

Nadine Velazquez as Maria

Kenneth Choi as Takada

Andrea Roth as Jenny Crawford

Sung Kang as Special Agent Goi

Mathew St. Patrick as Special Agent Wick

Terry Chen as Special Agent Tom Lone

Steph Song as Diane Lone

Kennedy Montano as Ana Chang

Kane Kosugi as Temple Garden Warrior

Eric Keenleyside as Leevie

Annika Foo as Amy Lone

Nicholas Elia as Daniel Crawford

Tim Perez as Mexican Interpol Agent

Peter Shinkoda as Harbor Yanagawa Shatei

Johnson Phan as Joey Ti

Larry Lam as Yanagawa Assassin

Warren Takeuchi as Harbor Yanagawa Lt.

Don Lew as Yakuza Warrior

John Novak as Captain Andrews

Randy Lee as Zero Yakuza-Making Love

Jennifer Chang as Zero Teenage Girl

Lucy Lu as Zero Hooker

Jennifer Chung as Teenage Girl

Aaron Au as Eddie

Wilken Yam as Wong

Hiro Kanagawa as Yoshido

Jung-Yul Kim as Yuzo

Tran Thi Thu as Benny's Girl

Mitchell A. Lee Yuen as Freelancer #1

Brian Ho as Freelancer #2

Nadia Farès as Jade Agent Kinler

Aaron Pearl as Jade Agent Clark

Bruce Bellocchi as Sam Nolan

Allan Lysell as Cabin Policeman

Ildiko Ferenczi as Hot Girl (uncredited)

Meghan Flather as Call Girl