Robert De Niro as Wayne "Mad Dog" Dobie

Uma Thurman as Glory

Bill Murray as Frank Milo

David Caruso as Mike

Mike Starr as Harold

Tom Towles as Andrew the Beater

Kathy Baker as Lee

Derek Anunciation as Shooter

Doug Hara as Driver

Evan Lionel as Dealer in Car

Anthony Cannata as Pavletz

J.J. Johnston as Shanlon

Guy Van Swearingen as Cop

Jack Wallace as Tommy the Bartender

Richard Belzer as M.C. / Comic

Clem Caserta as Guy at Table

Fred Squillo as Frank's Gang

Chuck Parello as Frank's Gang

Tony Fitzpatrick as Detective at Crime Scene

Eric Young as Detective at Crime Scene

Bruce Jarchow as Detective at Crime Scene

Bob Rice as Uniform Cop

William King as Dealer in Park

Kevin Hurley as Dealer in Park

Richard Price as Detective in Restaurant

John Polce as Dispatcher

Dick Sollenberger as Saul

Paula Killen as Irene

Eddie Bo Smith Jr. as Big John

Suzy Brack as Student (uncredited)

Tony Castillo as Maitre D' (uncredited)

Brian Reed Garvin as Detective Burns (uncredited)

Frankie 'Hollywood' Rodriguez as Bar Patron (uncredited)