Andy García as Michael Green

Meg Ryan as Alice Green

Tina Majorino as Jessica Green

Philip Seymour Hoffman as Gary

Mae Whitman as Casey Green

Ellen Burstyn as Emily

Eugene Roche as Walter

Gail Strickland as Pam

Susanna Thompson as Janet

Lauren Tom as Amy

Steven Brill as Madras Tie Guy

Erinn Canavan as Shannon

LaTanya Richardson Jackson as Dr. Gina Mendez

Bari K. Willerford as Malcolm

James Jude Courtney as Earl

Jacques De Groot as Guy in the Back

Anne Ohliger as Jess - 4 Yrs. Old

Tony Montero as Bartender

Cynthia Mace as De-tox Nurse

Jennie Yee as Vu

William Frankfather as Al-anon Leader

Ellen Geer as Woman at Al-Anon

Angelina Fiordellisi as Joanna

Elizabeth Lang as AA Woman

Syd Field as Patient #1

Peer Ebbighausen as Patient #2

Ronald Bass as AA Man #1

Joe Drago as AA Man #2

Andrew Magarian as AA Man #3

Amy Treese as AA Woman #2

Brandis Kemp as AA Woman #3

Judith Friend as AA Woman #4

Deana Kobrynski as AA Woman #5

Rico E. Anderson as Barfly (uncredited)

Lena Banks as Nurse (uncredited)

Richard Bradford as Angry Man Watching TV (uncredited)

Al Franken as Co-Pilot (uncredited)

Craig Richards as Patient #3 (uncredited)

Reed Rudy as Angry Guy (uncredited)

Joseph Quinn Simpkins as Barfly (uncredited)