Josh Brolin as George W. Bush

Colin Hanks as Speechwriter #1

Toby Jones as Karl Rove

Dennis Boutsikaris as Paul Wolfowitz

Jeffrey Wright as Colin Powell

Thandiwe Newton as Condoleezza Rice

Scott Glenn as Donald Rumsfeld

Richard Dreyfuss as Dick Cheney

Bruce McGill as George Tenet

Wes Chatham as Fraternity Enforcer

Jesse Bradford as Fraternity President

Sean Stone as Fraternity Pledge #1

Ben Mayer as Fraternity Pledge #2

James Cromwell as George H.W. Bush

Juan Gabriel Pareja as Oil Worker

Shea Lewis as Oil Rig Driller

Randal Reeder as Oil Rig Foreman

Marley Shelton as Fran

Litt Martin as 1971 Houston Oilman #1

James Ron Parker as 1971 Houston Oilman #2

Michael Gaston as General Tommy Franks

Keenan Harrison Brand as Marvin Bush

Ellen Burstyn as Barbara Bush

Jason Ritter as Jeb Bush

Bryan Massey as Skeeter

Noah Wyle as Don Evans

Bill Jenkins as Jim Sale

Brent Sexton as Joe O'Neill

Jonathan Breck as Corn Dog

Jennifer Sipes as Suzie Evans

Jonna Juul-Hansen as Jan O'Neill

Elizabeth Banks as Laura Bush

Paul Rae as Kent Hance

David Born as Texas Debate Moderator

John Buffalo Mailer as Speechwriter #2

James Martin Kelly as NSC Official

Rob Corddry as Ari Fleischer

William Lanier as Resort Waiter

Stacy Keach as Rev. Earle Hudd

Gregory Alan Williams as Evangelical Minister

Jon Michael Davis as 1988 Campaign Aide #1

Andrew Sensenig as Texas Reporter #1

Gabriela Ostos as Texas Reporter #2

Lisa Fairchild as Texas Reporter #3

Paul T. Taylor as Texas Reporter #4

Halley Rachal as Park Bench Voter #1

Dottie McWhiney as Park Bench Voter #2

Ronan Summers as CIA Official

John Neisler as Cheney's Lawyer

Ioan Gruffudd as Prime Minister Tony Blair

Charles Fathy as Pres. Jacques Chirac (voice)

Jim Garrity as TV Commentator #1

Anne Pressly as TV Commentator #2

Randall Newsome as Paul Bremer

Jewel Williams as Legless Soldier

Oscar Contreras as Burned Soldier

Tom Kemp as Dr. David Kay

Teresa Cheung as Miss China

Brad Sham as White House Reporter