Gerard Butler as Dracula

Christopher Plummer as Matthew Van Helsing

Jonny Lee Miller as Simon Sheppard

Justine Waddell as Mary Heller

Vitamin C as Lucy Westerman

Jennifer Esposito as Solina

Omar Epps as Marcus

Sean Patrick Thomas as Trick

Danny Masterson as Nightshade

Lochlyn Munro as Eddie

Tig Fong as Dax

Tony Munch as Charlie

Jeri Ryan as Valerie Sharpe

Shane West as JT

Nathan Fillion as Father David

Tom Kane as Anchor Man

Jonathan Whittaker as Gautreaux

Robert Verlaque as Dr. Seward

Randy Butcher as Stakeman #1

Bill Davidson as Stakeman #2

Peter Cox as Stakeman #3

Chris Lamon as Stakeman #4

Herb Reischl Jr. as Stakeman #5

Duncan McLeod as Stakeman #6

Wayne Downer as Desk Guard

Robert Racki as Door Guard

William Prael as Parade Cop

Kaaron Briscoe as Teen Co-Worker

Scarlett Huntley as Blood Doll

Harold Short as Black Angel of Death

David J. Francis as Jesus

Shimmy Silverman as Barker