Jerry O'Connell as Charlie Carbone

Anthony Anderson as Louis Booker

Estella Warren as Jessie

Christopher Walken as Salvatore 'Sal' Maggio

Michael Shannon as Frankie Lombardo

Marton Csokas as Mr. Smith

Dyan Cannon as Anna Carbone

Frank Welker as Jack's Vocal Effects

John McNeill as Customs Officer

Bill Hunter as Blue

Tony Nikolakopoulos as Sal's Capo

David Ngoombujarra as Mr Jimmy

Denise Roberts as Tansy

Lara Cox as Cute Girl on Plane

Damien Fotiou as Baby J

Helen Thomson as TV Announcer

Christopher James Baker as Crumble

Antonio Vitiello as Toot

Marco Sellitto as Blasta

Ryan Gibson as Hoon

Adam Garcia as Kangaroo Jack/"Jackie Legs" (Uncredited0

Robert Reid as Young Charlie Carbone

Shawn H. Smith as Young Louis Booker