Christopher Lee as Sherlock Holmes

Patrick Macnee as Dr. Watson

Morgan Fairchild as Irene Frances Adler

John Bennett as Sigmund Freud

Michael Siberry as Franz Winterhauser

Dominic Jephcott as Major Von Bork

Frank Middlemass as Dr. Froelich

James Bree as Franz Dietrich

Tom Chadbon as Zygovich

Paul Humpoletz as Hugo Oberstein

Tom Lahm as Elliott Ness

Ronald Hines as Reginald Cholmondley

Nicholas Gecks as Michael Simpson-Makepeace

Jenny Quayle as Violet Cholmondley

Charlotte Attenborough as Margaret Froelich

Kalman Glass as Franz Zimmer

Robert Rietti as Franz Hoffman

Terence Beesley as Serge Duvok

Patrick Monckton as Laszlo Karparti

Leon Lissek as Stage Door-Keeper

Cyril Shaps as Franz Joseph

Guy Scantlebury as Captain Melbury

Jerome Willis as Mycroft Holmes

Margaret John as Mrs. Hudson

Michael McStay as Inspector Schmidt

Engelbert Humperdinck as Eberhardt Bohm