Meg Ryan as Frannie Avery

Mark Ruffalo as Giovanni A. Malloy

Jennifer Jason Leigh as Pauline

Nick Damici as Detective Rodriguez

Sharrieff Pugh as Cornelius Webb

Heather Litteer as Angela Sands

Michael Nuccio as Frannie's Young Father

Allison Nega as Young Father's Fiancee

Dominick Aries as Attentive Husband

Susan Gardner as Perfect Wife

Daniel T. Booth as Luther Wilker Red Turtle Bartender

Yaani King Mondschein as Frannie's Student

Frank Harts as Frannie's Student

Sebastian Sozzi as Frannie's Student

Zach Wegner as Frannie's Student

Patrice O'Neal as Hector

Arthur J. Nascarella as Captain Crosley

Funda Duval as Baby Doll Bartender

Theo Kogan as Baby Doll Bartender

Sandy Vital as Baby Doll Dancer

Sharon Riggins as Baby Doll Dancer

Karen Riggins as Baby Doll Dancer

Nancy La Scala as Baby Doll Dancer

Ami Goodheart as Baby Doll Dancer

Panicker Upendran as Taxi Driver

Kendra A. Zimmerman as Cafe Waitress

Michelle Hurst as Teacher at Frannie's School

Sunrise Coigney as Frannie's Young Mother

Hal Sherman as Forensic Detective

Dana Lubotsky as Laundry Room Murder Witness

Jacinto Taras Riddick as Detective in Precinct

James Firo as Detective Halloran

Cordell Clyde as Informer

Tim House as Baby Doll Bar Customer

Julius LeFlore as Cursing Motorist

Vinny Vella as Concerned Bystander

Kevin Bacon as John Graham (uncredited)

Skippy D as Business Owner (uncredited)

Michelle DiBenedetti as Street Walker (uncredited)

Sein Gay as Patron (uncredited)

Michael Ienna as Larry (uncredited)

Lou Martini Jr. as Sleazy Bar Patron (uncredited)

Susan Trishel Monsøn as Subway Rider (uncredited)

Nicole Spruill as Girl at Bar (uncredited)