Jack Black as Satan

Robert Timothy Smith as Liam Turner

Keegan-Michael Key as Dr. Finkleman

Brianne Howey as Molly Turner

Hayes MacArthur as Bill Turner

P.J. Byrne as Mr. Charles

Jaden Carson Baker as Gibby

Kai Cech as Emma

Post Malone as Post Malone

Gavin Munn as Aidan

Cate Freedman as Crossing Guard

Ben Stiller as Lucifer (uncredited)

Kyle Gass as Science Teacher

Lee Reyes as Lee

Bash Hagelin as Joey

Bryson Dean Haney as Grayson

Lindsay Rootare as Technician

Luke Chiappetta as Jock

Greg Clarkson as Male Newscaster

Maiya Moran as Female Newscaster

Leo Easton Kelly as Spencer

Tierre Turner as Blitzen (voice)

Carole Kaboya as Little Kid’s Mom

Travon McEntyre as Male Nurse

Izzy Herbert as Flirty Girl

Selah Kimbro Jones as Attractive Girl

Abe Farrelly as Tattoo Tony