Maggie Lawson as Nancy Drew

Jill Ritchie as Bess

Lauren Birkell as George

Marieh Delfino as Teeny

Charlie Finn as Hank

Heath Freeman as Det. Patrick Daly

Brian J. White as Franklin 'Sweet Money' Roosevelt Sanderson

James Avery as Prof. Shifflin

Brett Cullen as Carson Drew

Kevin Tighe as Coach Jeffries

Sabine Singh as Allison Price

Dale Midkiff as Jimbo Mitchell

Jenny O'Hara as Hannah Green

Nick Stabile as Ned Nickerson

Hoku as Bitsy

Joanna Canton as Sue

Michelle Morgan as Jaclyn Kennedy Calberson

Claudette Sutherland as Waitress

Ellen Geer as Librarian

Dayton Callie as Desk Cop #1

Wiley M. Pickett as Desk Cop #2

Sloan Robinson as Head Nurse

Todd Sandler as Security Guard

Giselle Loren as Police Officer

Jeff D'Agostino as Heavy Metal Kid

Andrew Leeds as Newspaper Kid