Tony Shalhoub as Adrian Monk

Traylor Howard as Natalie Teeger-Albright

Jason Gray-Stanford as Randall 'Randy' Disher

Melora Hardin as Trudy Monk

Héctor Elizondo as Dr. Neven Bell

Ted Levine as Leland Stottlemeyer

James Purefoy as Rick Eden

Caitlin McGee as Molly Evans

Austin Scott as Griffin

Emma Ishta as Skyler

Paulino Nunes as Lucas Kubrick

Raven Dauda as Captain Lisa Rudner

Brooke Adams as Beth

Richard Kind as Funeral Director #1 / #2

Gurdeep Ahluwalia as Anchorman

Bitty Schram as Sharona Fleming

Adam Bernett as Jumper Friend

Daniel DeSanto as Engineer

Pip Dwyer as Sgt. Platt

Donna Garner as Lawyer

Jamaal Grant as Mission Director

Alexander Nunez as Assistant

Madison Seguin as Erica

Mike 'Nug' Nahrgang as Man on Elevator

David Webster as Quinlan

Nicole Passmore as Woman Passenger

Jeff Sinasac as Male Passenger

Adriano Sobretodo Jr. as Family Friend

Chantria Tram as Bystander

Luke Marty as Eden Security Guard #1

Quenton Rose as Eden Security Guard #2

Melody Shang as Ghost Victim #1

MacKenzie Boyd-Garrison as Ghost Victim #2

John-Michael Scapin as Ghost Victim #3

Bryan Barnes as Ghost Victim #4

Rachel MacMillan as Ghost Victim #5

Adam Chuckryk as Ghost Victim #6

Jamaica Fraser as Young Female Ghost

Perry Perlmutar as Various Guest #1

Madeleine Donohue as Impatient Guest

Yuvaraja Bhide as Impatient Guest #2