Alan Rickman as Hilly Kristal

Rupert Grint as Cheetah Chrome

Malin Åkerman as Debbie Harry

Johnny Galecki as Terry Ork

Stana Katic as Genya Ravan

Ashley Greene as Lisa Kristal

Justin Bartha as Stiv Bators

Ryan Hurst as Mad Mountain

Kyle Gallner as Lou Reed

Taylor Hawkins as Iggy Pop

Josh Zuckerman as John Holmstrom

Peter Vack as Legs McNeil

Parker Grant as Baby Hilly

Arthur Bridgers as Shamal Kristal

Danielle Shaw as Young Bertha

Holly Hubbell as Sarah Brown

B. Todd Johnston as Benjamin Brown

Freddy Rodríguez as Idaho

Tom Nowicki as Palace Bartender

Estelle Harris as Bertha Kristal

Donal Logue as Merv Ferguson

Max Reindhardsen as Tom Verlaine

Luke Dressler as Richard Lloyd

Richard de Klerk as Taxi

Evan Alex Cole as Richard Hell

Ahna O'Reilly as Mary Harron

Bradley Whitford as Nicky Grant

Joel David Moore as Joey Ramone

Steven Schub as Dee Dee Ramone

Julian Acosta as Johnny Ramone

Caleb McCotter as Wayne County

Bronson Adams as Johnny Blitz

Vincenzo Hinckley as Da Thug

Cheetah Chrome as Cabbie

Keene McRae as Sting

Mickey Sumner as Patti Smith

Dominic Bogart as Michael Sticca

Jared Carter as David Byrne

Kamille Dawkins as Bank Teller

Katherine DuBois as Genya's Friend

James Edwards as Psychotic Fan

Darin Heames as Bert

Abby Leigh Huffstetler as Tina Weymouth

Bob Lipka as Ye Ol' Farmer

Michael Massee as Officer Stan

Aaron Munoz as Palace Hotel Manager

Juan Piedrahita as Angry Hombre #1

Richard Marrero as Angry Hombre #2

Benjamin Frankenberg as John Piccolo