Vince Vaughn as Norman Bates

Anne Heche as Marion Crane

Julianne Moore as Lila Crane

Viggo Mortensen as Samuel 'Sam' Loomis

William H. Macy as Milton Arbogast

Robert Forster as Dr. Simon

Philip Baker Hall as Sheriff Chambers

Anne Haney as Mrs. Chambers

Chad Everett as Tom Cassidy

Rance Howard as Mr. Lowery

Rita Wilson as Caroline

James Remar as Patrolman

James Le Gros as California Charlie

Flea as Bob Summerfield

Gus Van Sant as Man Talking to Man in Cowboy Hat (uncredited)