Jeff Daniels as Charles Driggs

Melanie Griffith as Audrey Hankel

Ray Liotta as Ray Sinclair

George 'Red' Schwartz as Counter Man

Margaret Colin as Irene

Leib Lensky as Frenchy

Tracey Walter as The Country Squire

Maggie T. as Country Squire Bulldog

Patricia Falkenhain as Charlie's Secretary

Sandy McLeod as Graves' Secretary

Robert Ridgely as Richard Graves

Buzz Kilman as TV Newscaster

Kenneth Utt as Dad

Adelle Lutz as Rose

Charles Napier as Irate Chef

Jim Roche as Motel Philosopher

John Sayles as Motorcycle Cop

John Waters as Used Car Guy

The Texas Kid as Hitchhiking Cowboy

Byron D. Hutcherson as Hitchhiking Kid

Eleana Hutcherson as Hitchhiking Kid

Thomas Cavano as Guitar Player

Dorothy Demme as Junk Store Gal

Emma Byrne as Junk Store Gal

Dana Preu as Peaches

Mary Ardella Drew as Donna Penski

Joseph Lee Davis as James Williams

Edward Saxon as Kevin Stroup

James Hurd as Stylish Reunion Couple

Joanna Kitchen-Hurd as Stylish Reunion Couple

Jack Gilpin as Larry Dillman

Su Tissue as Peggy Dillman

Gary Goetzman as Guido Paonessa

Chloe Amateau as Chloe

Dung Chau as Robbery Victim

Steven Scales as Nelson

John Montgomery as Harmonica Slim

Kristin Olsen as Tracy

Heather Shaw as Choir Girl

Vic Blair as Cowboy Maitre d'

D. Stanton Miranda as Darlene

Ding-a-Ling as Motorcycle Dog

Johnny Marrs as Motorcycle Driver

George Henry Wyche Jr. as Police Officer

Marilee K. Smith as Police Officer

Jeffrey R. Rioux as Police Officer

Jeff Herig as Police Officer

Gil Lazier as Homicide Detective

Anna Thomson as The Girl in 3F

'Sister' Carol East as Dottie