Leonardo DiCaprio as Teddy Daniels

Mark Ruffalo as Chuck Aule

Ben Kingsley as Dr. Cawley

Max von Sydow as Dr. Naehring

Michelle Williams as Dolores

Emily Mortimer as Rachel 1

Patricia Clarkson as Rachel 2

Jackie Earle Haley as George Noyce

Ted Levine as Warden

John Carroll Lynch as Deputy Warden McPherson

Elias Koteas as Laeddis

Robin Bartlett as Bridget Kearns

Christopher Denham as Peter Breene

Nellie Sciutto as Nurse Marino

Joseph Sikora as Glen Miga

Curtiss Cook as Trey Washington

Raymond Anthony Thomas as Orderly Ganton

Joseph McKenna as Inmate Billings

Ruby Jerins as Little Girl

Tom Kemp as Ward C Guard

Bates Wilder as Ward C Guard

Lars Gerhard as Dying Commandant

Matthew Cowles as Ferry Captain

Jill Larson as Manacled Woman

Ziad Akl as Tattoo'd Man

Dennis Lynch as Red-Haired Man

John Porell as Wild-Eyed Man

Aidan Cole Mitchell as Younger Boy

Drew Beasley as Younger Boy

Joseph P. Reidy as Operator

Bree Elrod as Female Patient

Thomas B. Duffy as Guard

Ken Cheeseman as Doctor

Steve Witting as Doctor

Michael E. Chapman as Patient

Darryl Wooten as Orderly

Michael Byron as McPherson's Driver

Gary Galone as Gate Guard

Gabriel Hansen as Young Guard

Harrison Young as Psychiatric Patient (uncredited)

John Franchi as Criminally Insane Inmate (uncredited)