Charles Grodin as George Newton

Bonnie Hunt as Alice Newton

Dean Jones as Dr. Varnick

Nicholle Tom as Ryce

Christopher Castile as Ted

Sarah Rose Karr as Emily

Oliver Platt as Harvey

Stanley Tucci as Vernon

Laurel Cronin as Devonia Peet

David Duchovny as Brad

Patricia Heaton as Brie

O-Lan Jones as Biker Woman

Nancy Fish as Miss Grundel

Craig Pinkard as Homeless Man

Robi Davidson as Mark

Sherri Paysinger as Reporter

Patrick LaBrecque as Bully #1

Jacob Kenner as Bully #2

Matthew Brooks as Bully #3

Chris Little as Newsreader

Lisa Paige Robinson as Donna

Cory Danziger as Mark's Friend

Colleen O'Hara as Young Woman

Nicolas Mize as Young Man

Maxine Elliott Hicks as Old Woman

Stephanie Durrer as Young Woman

Cirroc Lofton as Skateboarder #1

Chad Morton as Skateboarder #2

Melora Walters as Pet Shop Owner

Holly Wortell as Nurse #2

Lorraine Marga as Mother at Pet Store

Joseph Gordon-Levitt as Student #1

Andres McKenzie as Student #2

Richard Portnow as Ammunition Company Representative (uncredited)