Oscar Isaac as Jesus Christ (voice)

Kenneth Branagh as Charles Dickens (voice)

Uma Thurman as Catherine Dickens (voice)

Pierce Brosnan as Pontius Pilate (voice)

Roman Griffin Davis as Walter Dickens (voice)

Forest Whitaker as Peter (voice)

Ben Kingsley as High Priest Caiaphas (voice)

Mark Hamill as King Herod (voice)

Ava Sanger as Mary Dickens (voice)

Jim Cummings as James the Greater / Pharisee Hillel (voice)

Dee Bradley Baker as Willa the Cat (voice)

Fred Tatasciore as Pharisee Eleazar (voice)

James Arnold Taylor as Melchior / Matthew / Thomas / Phillip / Young Jesus (voice)

Vanessa Marshall as Mary of Bethany / Adulteress (voice)

Mick Wingert as Gaspar / Pharisee Mahaliell (voice)

Imari Williams as Balthazar / Bartholomew (voice)

Frank Todaro as Gestas (voice)

Millicent Miereanu as Martha (voice)