Nicholas Rowe as Sherlock Holmes

Alan Cox as John Watson

Sophie Ward as Elizabeth Hardy

Anthony Higgins as Professor Rathe

Susan Fleetwood as Mrs. Dribb

Roger Ashton-Griffiths as Det. Sgt. Lestrade

Matthew Ryan as Dudley's Friend

Earl Rhodes as Dudley

Freddie Jones as Chester Cragwitch

Patrick Newell as Bentley Booster

Nadim Sawalha as Khasek - Lower Nile Tavern Owner

Nigel Stock as Rupert T. Waxflatter

Brian Oulton as Master Snelgrove

Donald Eccles as The Reverend Duncan Nesbitt

Matthew Blakstad as Dudley's Friend

Jonathan Lacey as Dudley's Friend

Walter Sparrow as Ethan Engel

Roger Brierley as Mr. Holmes

Vivienne Chandler as Mrs. Holmes

Lockwood West as Curio Shop Owner

John Scott Martin as Cemetery Caretaker

George Malpas as School Porter

Willoughby Goddard as School Reverend

Michael Cule as Policeman with Lestrade

Ralph Tabakin as Policeman in Shop Window

Nancy Nevinson as Hotel Receptionist

Michael Hordern as Older Watson (voice)

Grant Burns as Schoolboy (uncredited)

George Lane Cooper as Acolyte (uncredited)

Salo Gardner as Chestnut Seller (uncredited)

Lew Hooper as Restaurant Patron (uncredited)

Royston Munt as Footman (uncredited)

Henry Roberts as School Master (uncredited)

Fred Wood as Patron (Lower Nile Tavern) (uncredited)