Jerry O'Connell as Joe

Megan Ward as Lily Dougherty

Billy West as Ralph Roach (voice)

Reginald Hudlin as Rodney Roach (voice)

Willi One Blood as Complaint Handler

Tracy Vilar as Complaint Handler

Sandra 'Pepa' Denton as Blank

Robert Vaughn as Senator Dougherty

Shiek Mahmud-Bey as Vladimir Bianco

Jon Spencer as Boss Hog Band Member

Paul Bartel as NEA Scout

Tommy Hollis as Boss Plumber

Don Ho as Alberto Bianco

Jim Sterling as Jesus Bianco / Voice of Cockroach

David Huddleston as P.I. Smith

Vincent Pastore as Apartment Broker #2

Scott Bigelow as Boss Construction

Moby as Club DeeJay

Dave Chappelle as Cockroach (voice)

Godfrey as Cockroach (voice)

Tim Blake Nelson as Cockroach (voice)

BD Wong as Cockroach (voice)

Lord Kayson as Stick-Up Man #2

Alex Molina as Stick-Up Man #3

Frank Bello as Stick-Up Man #1

Jim Turner as Walter Shit / Voice of Cockroach

Wayman Ezell as Apartment Broker #1

Rick Aviles as Cockroach (voice)

Mark Rosenthal as Cockroach (voice)

Nick Zedd as Pizza Couple

Solange Monnier as Pizza Couple

Roy Milton Davis as Complaint Handler

William Preston as Complaint Handler

Christopher Durang as Boss Clergy

Glenn Kubota as Lab Manager

Desiree Casado as Girl at Play

Edward Rosado as Boy at Play

Vebe Borge as Cockroach (voice)

Dale Goodson as Boss Clown

Peter Yoshida as Zipp Code Customer

Stewart Russell as Zipp Code Manager

Cristina Martinez as Boss Hog Band Member

Jens Jurgensen as Boss Hog Band Member

Hollis Yungblut as Boss Hog Band Member

Jennie Moreau as Cockroach (voice)

William Wegman as Distinguished Man with Dog

Rae C. Wright as Movie Goer

Toukie Smith as Head User

Patricia O'Connell as Ms. Featherstone

Fanni Green as Counsel

Kevin Weist as Cockroach (voice)

Salvatore Paul Piro as Sal

Peggy Healey as Counsel

Michael Mandell as Complaint Handler

Cynthia Neilson as Dangling Woman

Geoffrey Whelan as Cockroach (voice)