Jennifer Lopez as The Artist

Ben Affleck as Rex Stone / Biker

Idaliz Christian as Flower Farmer

Fat Joe as Therapist

Matthew Law as The Cynic / Mike

Brandon Delsid as The Lover

Alix Angelis as The Quiet One

Malcolm Kelner as The Realist

Ashley Versher as The Idealist

Danielle Larracuente as The Fighter

Gilbert Saldivar as The New Guy

Jane Fonda as Sagittarius

Trevor Noah as Libra

Kim Petras as Virgo

Post Malone as Leo

Keke Palmer as Scorpio

Sofía Vergara as Cancer

Jenifer Lewis as Gemini

Jay Shetty as Aries

Neil deGrasse Tyson as Taurus

Sadhguru as Pisces

Tony Bellissimo as Husband #1

Derek Hough as Husband #2

Trevor Jackson as Husband #3

Carlito Olivero as Mr. Young Guy

Paul Raci as Group Leader

Bella Gagliano as Little Jenny

Maya R Marquez as Little Jenny Sister

Jocelyn Marie as Bronx Crew

Greg Roman as Bronx Crew

Alexander Pelaez as Bronx Crew

Alex West as Louis

Snoop as Puppy

Bosco as Dog