Jennifer Morrison as Amy Mayfield

Matthew Davis as Travis / Trevor

Hart Bochner as Professor Solomon

Loretta Devine as Reese

Joey Lawrence as Graham

Anson Mount as Toby

Jessica Cauffiel as Sandra

Anthony Anderson as Stan

Michael Bacall as Dirk

Eva Mendes as Vanessa

Marco Hofschneider as Schorm "Simon" Jabuscko

Derek Aasland as P.A. Kevin

Jacinda Barrett as Lisa

Peter Millard as Dr. Richard Fain

Chas Lawther as Dean Patterson

Chuck Campbell as Geek in Plane

Yani Gellman as Rob

Jeannette Sousa as Libby

Rebecca Gayheart as Brenda Bates

Bianca Muller as Student Screamer

Jenny Kim as Student Screamer