Tim Roth as Stretch

Tupac Shakur as Spoon

Thandiwe Newton as Cookie

Charles Fleischer as Mr. Woodson

Vondie Curtis-Hall as D-Reper

Howard Hesseman as Blind Man

James Pickens Jr. as Supervisor

Tom Towles as D-Reper's Henchman

Bokeem Woodbine as Mud (uncredited)

John Sayles as Cop #1

Eric Payne as Cop #2

Tom Wright as Koolaid

James Shanta as Patrolman #1

Jim O'Malley as Patrolman #2

George Poulos as Chuck

Debbie Zaricor as Clerk

Mik Scriba as Officer #1

Lucy Liu as Cee-cee

Richmond Arquette as Resident Doctor

Billie Neal as Medicaid Woman #1

Debra Wilson as Medicaid Woman #2

Rusty Schwimmer as Nurse

Elizabeth Peña as Admissions Person

Joey Dente as Vendor

Darryl Jones as Panhandler

Jasen Govine as Medicaid Security Guard

Tim Truby as Man with Directions

Venessia Valentino as Woman in ER

Ron Cummins as Man in ER

Brad Spencer as Paramedic #1

Rory J. Shoaf as Paramedic #2

Tracy Vilar as Screaming Woman

Roslyn McKinney as Female Clerk

Roderick Garr as Welfare Security Guard

William Long Jr. as Right Wing TV Show Host

Mark Ericson as Bill the Anchor Man

Tonia Rowe as Woman on TV

Lynn Blades as Alexia Cruz

Kasi Lemmons as Madonna

Henry Hunter Hall as Child