Ed Harris as Jackson Pollock

Marcia Gay Harden as Lee Krasner

Tom Bower as Dan Miller

Jennifer Connelly as Ruth Kligman

Bud Cort as Howard Putzel

John Heard as Tony Smith

Val Kilmer as Willem DeKooning

David Leary as Charles Pollock

Robert Knott as Sande Pollock

Stephanie Seymour as Helen Frankenthaler

Molly Regan as Arloie Pollock

Sada Thompson as Stella Pollock

Eulala Scheel as Arloie's Baby

Matthew Sussman as Reuben Kadish

Amy Madigan as Peggy Guggenheim

Everett Quinton as James Johnson Sweeney

Annabelle Gurwitch as May Rosenberg

John Rothman as Harold Rosenberg

Kenny Scharf as William Baziotes

Tom McGuinness as Franz Kline

Jeffrey Tambor as Clem Greenberg

Katherine Wallach as Barbara Kadish

Cassandra Clewicki as Kadish Child

Sloane Shelton as Dot Miller

Eduardo Machado as Alfonso Ossorio

Moss Roberts as Ted Dragon

Robert O'Neill as Herbert Matter

Isabelle Townsend as Mercedes Matter

Jennifer Piech as Young Redhead

Rebecca Wisocky as Dorothy Seiberling

Linda Emond as Martha Holmes

Tony Palazzolo as Delivery Man

Barbara Garrick as Betty Parsons

David Cale as William Wright

Claire Beckman as Vita Peterson

Stephen Beach as Jay Pollock

Jill Jackson as Alma Pollock

Donna Mitchell as Elizabeth Pollock

Sondra Jablonski as Jeremy Pollock

Frank Wood as Frank Pollock

Julie Anna Rose as Marie Pollock

Kyle Timothy Smith as Jonathan Pollock

April Petroski as Karen Pollock

Nicholas Petroski as Jason Pollock

Noah Petroski as Jason Pollock

Norbert Weisser as Hans Namuth

Sally Murphy as Edith Metzger

Bob L. Harris as Veterinarian

Jake as Young Gyp

Trecker as Old Gyp

John Madigan as News Broadcaster (voice)

Matthew Hart Landfield as Newspaper Boy (uncredited)

John Nesci as East Hampton Police Officer (uncredited)