Benedict Cumberbatch as Theo

Olivia Colman as Ivy

Andy Samberg as Barry

Kate McKinnon as Amy

Allison Janney as Eleanor

Belinda Bromilow as Janice

Sunita Mani as Jane

Ncuti Gatwa as Jeffrey

Jamie Demetriou as Rory

Zoë Chao as Sally

Will Smith as Derek

Hala Finley as Hattie Rose (Older)

Delaney Quinn as Hattie Rose (Younger)

Wells Rappaport as Roy Rose (Older)

Ollie Robinson as Roy Rose (Younger)

Margaret Clunie as Sophie

Akie Kotabe as Alan

Emily Piggford as Lily

Matt Corboy as HAL (voice)

Ranjani Brow as News Anchor

Robin Atkin Downes as Boss

Ollie Dabbous as Ollie Dabbous

Caroline Partridge as Sylvia (Food Critic)

Paul Pape as Commercial Announcer

Jude Coward Nicoll as Teenager on Airplane