Ray Stevenson as Frank Castle / The Punisher

Dominic West as Billy "The Beaut" Russoti / Jigsaw

Julie Benz as Angela Donatelli

Colin Salmon as Paul Budiansky

Doug Hutchison as James Russoti / "Loony Bin Jim" / "LBJ"

Dash Mihok as Martin Soap

Wayne Knight as Linus Lieberman / Micro

Stephanie Janusauskas as Grace Donatelli

Mark Camacho as Carmine "Pittsy" Gazzera

Keram Malicki-Sánchez as "Ink" Gazzera

Romano Orzari as Nicky Donatelli

Carlos Gonzalez-Vio as Carlos

T.J. Storm as Maginty

David Vadim as Cristu Bulat

Aubert Pallascio as Tiberiu

Edward Yankie as Father Mike

Larry Day as Agent Miller

Ron Lea as Captain Ross

Tony Calabretta as Saffiotti

Niko Nikolov as Pompiliu

John Dunn-Hill as Cesare

Linda E. Smith as Mrs. Cesare

Bjanka Murgel as Arm Candy

Francis B. Goldberg as Mrs. Gordlock

Lynne De Bel as Micro's Mother

Cas Anvar as Plastic Surgeon

Mike Paterson as Motel Manager

Jon Barton as Ice Team Leader

Matt Holland as EMT

Pat Fry as Asylum Orderly

Robert Godley-Harrod as Priest

James Murray as Bodyguard #2

Brent Skagford as Waiter

Tracy Jerome Phillips as Harlem Gangleader

Miro Bedard as Frank's Son

Bill Hall as TV News Reporter

Andrew Farmer as Guard

Marco Desjean as Alpha Dog

Nick Sita as Nicki's Dad

Lise Sita as Nicki's Mom

Giovanni Cipolla as Wiseguy

Eric Dauphin as Cesare Wiseguy

Stéphane Byl as FBI Van Agent

Gerardo Lo Dico as NYPD Officer (uncredited)

Jean-Loup Yale as Mugger

Kane Chan as Banger #1

Steven P. Park as Banger #2

Matthew Chan as Banger #3 (uncredited)

Ethan Gold as Schoolboy

Oleg Popkov as Old Man

Eduardo Keller as Thug