Josh Zuckerman as Ian Lafferty

Amanda Crew as Felicia

Clark Duke as Lance

James Marsden as Rex Lafferty

Seth Green as Ezekiel

Alice Greczyn as Mary

Katrina Bowden as Ms. Tasty

Charlie McDermott as Andy

Mark L. Young as Randy

Cole Petersen as Dylan Lafferty

Dave Sheridan as Bobby Jo

Michael Cudlitz as Rick

Allison Weissman as Becca

Andrea Anders as Brandy

Kim Ostrenko as Mrs. Lafferty - Ian's Stepmom

Brett Rice as Mr. Lafferty - Ian's Dad

David Koechner as Hitchhiker

Caley Hayes as Sandy

Michele Simms as Drunk Amish Girl

Shay Roman as Pregnant Kristy

Bella Salinas as Fundraising Girl

John Ross Bowie as Dr. Clark Teddescoe

Keith Hudson as Angry Cop

Marianne Muellerleile as Grandma Prisoner

Jessica Just as Lindsay

Brian Posehn as Carney

Scott Klace as Lance's Dad

Allen Zwolle as Men's Room Predator

Cleo King as Abstinence Host

Josh Duarte as Brandy's Dad

Marcia Koch as Brandy's Mom

Ken Clement as Señor Donut Manager

Susie Abromeit as Cousin Tiffany

David Andrew Nash as Jail Cop

Giovanni Rodriguez as Thug Prisoner

Alan Lilly as Prisoner in Sports Jacket

Matthew Ramsey as Mall Prankster

Sasha Ramos as Kimberly

Sandra Ives as Seamstress

Olivia Nedza as Little Girl at Mall

Sam E. Goldberg as "Harsh" Guy

Rebecca Finer as Girl Entering Party

Drake Schirmer as Little Boy at Trailer Park

Massiel Perdomo as Undressed Abstinence Dancer

Brad Wilhite as Store Cashier

Dwayne Alexander Smith as Dwayne

Santara Sidersky as Angry Female Prisoner

Natalia Reagan as Pregnant Woman Prisoner

Kiki Harris as Female Cop

George Steward as Creepy Guy

Chris Charles Herbert as Jogger

Jimmy Baron as Church Dad

Kathryn Shasha as Church Mom

Darryll C. Scott as Angry Cop's Partner (as Darryll Scott)

Shelly Frasier as Dental Receptionist

Jeremy McGuire as Rex's Boyfriend

Pete Wentz as Pete Wentz (Fall Out Boy)

Joe Trohman as Joe Trohman (Fall Out Boy)

Patrick Stump as Patrick Stump (Fall Out Boy)

Andy Hurley as Andy Hurley (Fall Out Boy)

Kyle Gass as Trucker