Brittany Murphy as Krista

Rose Byrne as Leah

Toni Collette as Arden

Marcia Gay Harden as Melora

Mary Beth Hurt as Ruth

Piper Laurie as Arden's Mother

Kerry Washington as Rosetta

Josh Brolin as Tarlow

James Franco as Derek

Giovanni Ribisi as Rudy

Nick Searcy as Carl

Mary Steenburgen as Leah's Mother

Bruce Davison as Leah's Father

Carla Jimenez as Ashley's Caretaker

Donnie Smith as Cop #1

Michael Raysses as Cop #2

Earl Carroll as Reporter

Dorothy Beatty as Grocery Checker

Eva Loseth as Grocery Store Client

Joanie Tomsky as Therapist

Christopher Allen Nelson as Murray

Kate Mulligan as Party Girl

Dan Callahan as Storage Costumer #1

Gus Buktenica as Storage Costumer #2

Bobby Hosea as Detective

Lee von Ernst as Del

Gillian Pernoll as Ashley

Elizabeth Pernoll as Ashley

Daniel Leavitt as Candy Store Boy

Lea Nicole Carranza as Candy Store Girl

Amy Benedict as Candy Store Mom

Stephanie Mace as Mother

Paige Pelletier as Food Court Girl

Madison Pelletier as Food Court Girl

Dennis Keiffer as Tom