Dane Cook as Tank

Kate Hudson as Alexis

Jason Biggs as Dustin

Alec Baldwin as Professor Turner

Lizzy Caplan as Ami

Diora Baird as Rachel

Taran Killam as Josh

Riki Lindhome as Hilary

Nate Torrence as Craig

Mini Anden as Lizzy

Hilary Pingle as Claire

Malcolm Barrett as Dwalu

Faye Grant as Merrilee

Amanda Brooks as Carly

Richard Snee as Brian

Alberto Bonilla as Pedro

Sally Pressman as Courtney

Kate Albrecht as Laney the Babysitter

Rakefet Abergel as Heavily Pierced Kid

Andrew Lewis Caldwell as Sad Dork

Maureen Keiller as Seamstress

Tom Kemp as Priest

Tony V. as Chef Slava

Jacqui Holland as Kindly Stripper

Andria Blackman as Ms. Barber

Georgia Lyman as Hot Coed

Melina Lizette as Ms. Reiling

Josh Alexander as Burt

Jenny Mollen as Colleen

Eamon Brooks as Random Guy

Cyce Sadsad as Random Guy's Girl

Rob Rota as Lee

Edna Panaggio as Grandmother

Peggy McClellan as Angry Date Throwing Water

Brad Garrett as Irate Customer on Phone (voice) (uncredited)

Susan Garfield as Wedding Guest