Jack Black as Po (voice)

Bryan Cranston as Li (voice)

Dustin Hoffman as Shifu (voice)

Angelina Jolie as Tigress (voice)

J.K. Simmons as Kai (voice)

Jackie Chan as Monkey (voice)

Seth Rogen as Mantis (voice)

Lucy Liu as Viper (voice)

David Cross as Crane (voice)

Kate Hudson as Mei Mei (voice)

James Hong as Mr. Ping (voice)

Randall Duk Kim as Oogway (voice)

Steele Gagnon as Bao (voice)

Liam Knight as Lei Lei (voice)

Wayne Knight as Big Fun / Hom-Lee (voice)

Barbara Dirickson as Grandma Panda (voice)

Al Roker as Sum (voice)

Willie Geist as Dim (voice)

Fred Tatasciore as Master Bear (voice)

Pax Jolie-Pitt as Yoo (voice)

Kelly Cooney Cilella as Female Palace Goose (voice)

Stephen Kearin as Master Chicken (voice)

Mick Wingert as Farmer Goose / Farmer Rabbit (voice)

Ming Tsai as Ming (voice)

April Hong as Mrs. Chow (voice)

Knox Jolie-Pitt as Ku Ku (voice)

Zahara Jolie-Pitt as Meng Meng (voice)

Shiloh Jolie as Shuai Shuai (voice)

Jean-Claude Van Damme as Master Croc (voice)

Radzi Chinyanganya as Mi (voice)

Lindsey Russell as Peony (voice)

Joseph Izzo as Dumpling Record Pig (voice)

Lena Golia as Cheering Bunny (voice)

Gus Culligan as Panda Villager Kid (voice)

Mike Mitchell as Male Palace Goose / Smart Panda Villager (voice)