Emma Roberts as Nancy Drew

Max Thieriot as Ned Nickerson

Josh Flitter as Corky Veinshtein

Rachael Leigh Cook as Jane Brighton

Kay Panabaker as Georgie

Tate Donovan as Carson Drew

Marshall Bell as John Leshing

Daniella Monet as Inga Veinshtein

Kelly Vitz as Trish

Bruce Willis as Bruce (uncredited)

Laura Harring as Dehlia Draycott

Barry Bostwick as Dashiel Biedermeyer

Craig Gellis as Thug

Rich Cooper as Charlie

Amy Bruckner as Bess

Cliff Bemis as Chief McGinnis

David Doty as Father Murray

Pat Carroll as Landlady

Monica Parker as Hannah

Caroline Aaron as Barbara Barbara

Phil Abrams as Principal Fineman

Joanne Baron as Costume Lady

Ryan Raddatz as Assistant Director

Adam Goldberg as Arrogant Director Andy

Emmy Laybourne as File Lady

Elyssa Davalos as Twin Palms Manager

Kaitlyn Van Item as Allie Brighton

Robert Merrill as 'New Century' Actor

Chris Kattan as Burglar

Lindsay Sloane as Boutique Clerk

Amanda Alva as 'No' Woman

James Wing Woo as Chinese Priest in Movie