Robert Francis as Dr. Allen Seward

Donna Reed as Laurie MacKaye

May Wynn as Manyi-ten

Philip Carey as Capt. Peter Blake (as Phil Carey)

Onslow Stevens as Col. Ethan Waters

Peggy Converse as Mrs. Martha Walters

Roy Roberts as Sgt. Creever

Jack Kelly as Lt. Raymond

Stuart Randall as Chief Satanta

Eugene Iglesias as Red Leaf

Frank De Kova as Isatai

John War Eagle as Chief Quanah

Ralph Dumke as Dr. Gibson

James Best as Lt. Finlay (uncredited)