David Duchovny as Dr. Benjamin Marris

Olivia Thirlby as Samantha Marris

Lili Taylor as Hannah Marris

Millie Tresierra as Lindsay Porter

Trisha LaFache as Taylor

Laurence Leboeuf as Amelia

Kathleen Mackey as Gothic Librarian

Corey Sevier as Justin

Brendan Sexton III as Ethan

Jane Wheeler as Maggie Adams

Ashley Springer as Ian

Nicole Braber as Female Patient

Trent Pardy as Ski Shop Salesman

Julian Tassielli as ICU Doctor

Babs Chula as Psychiatrist

Joanna Noyes as Elizabeth - Hannah's Mother

Jay Brazeau as Doug Sullivan

Peter MacNeill as Dr. Christopher Bray

Macha Grenon as Tara Corbett

Bill Rowat as Teacher

Catherine Colvey as English Teacher

Bruce Ramsay as Daniel Harpin

Susan Glover as Condescending Woman

Linda Plamondon as Condescending Woman #2

Andrea Sadler as Condescending Woman #3

Dawn Ford as ICU nurse #1

Mariah Inger as ICU Nurse #2

Suzanna Lenir as ICU Nurse #3

Russell Yuen as ICU Doctor #2

Allan Yuk-lun Chou as ICU Doctor #3

Renee Madeline Le Guerrier as Hospital Receptionist

Lois Dellar as Aunt

Nick Kellis as Man Mourner

Ryan Tilson as Boy Mourner

Tristan D. Lalla as Fubu Boy

Steven Crowder as Classroom Boy

Robert Higden as Waiter

Lynne Adams as Resto Woman

Lucinda Davis as Paige - Ben's Assistant

Una Kay as Neighbour Wife

Mel Downey as Neighbour Husband

Cory Fantie as Patient #2

Bruce McKenzie as Patient #3

Abeille Gélinas as Girl with Justin

Dale Stuart Skinner as Priest

Carl Crevier as Lindsay's Husband

Henryk Vsakowski as Maggie's Husband

Li Li as Math Student

Frank Fontaine as Ned - Hannah's Father

Brandon Blue as Taylor's boyfriend (uncredited)