Elizabeth Taylor as Catherine Holly

Katharine Hepburn as Violet Venable

Montgomery Clift as Dr. Cukrowicz

Albert Dekker as Lawrence Hockstader

Mercedes McCambridge as Grace Holly

Gary Raymond as George Holly

Mavis Villiers as Miss Foxhill

Patricia Marmont as Nurse Benson

Joan Young as Sister Felicity

Maria Britneva as Lucy

Sheila Robbins as Dr. Hockstader's Secretary

David Cameron as Young Blonde Intern

Grace Denbigh Russell as Asylum Patient (uncredited)

Brenda Dunrich as Nurse (uncredited)

Eddie Fisher as Street Urchin (uncredited)

Frank Merlo as Audience Member at Operation (uncredited)

Sheila Raynor as Mother of Young Patient (uncredited)

Beatrice Shaw as Elderly Lady (uncredited)

Florence Stark as Patient (uncredited)

Julián Ugarte as Sebastian Venable (uncredited)

Gore Vidal as Audience Member at Operation (uncredited)

Rita Webb as Asylum Patient (uncredited)

Sandra White as Young Patient (uncredited)

Ian Wilson as Patient (uncredited)

Roberta Woolley as Nurse (uncredited)