Henry Winkler as Chuck Lumley

Michael Keaton as Bill Blazejowski

Shelley Long as Belinda Keaton

Gina Hecht as Charlotte Koogle

Pat Corley as Edward Koogle

Bobby Di Cicco as Leonard

Nita Talbot as Vivian

Basil Hoffman as Drollhauser

Tim Rossovich as Luke

Clint Howard as Jefferey

Joe Spinell as Manetti

Cheryl Carter as Tanya

Becky Gonzalez as Lupe

Corki Grazer as Sylvia

Jaid Barrymore as Joyce

Ava Lazar as Sharon

Ola Ray as Dawn

Cassandra Gava as J.J.

Ashley Cox as Jenny Lynn

Dawn Dunlap as Maxine

K.C. Winkler as Cheryl

Monique Gabrielle as Tessie

Richard Belzer as Pig

Beau Billingslea as Donny

Grand L. Bush as Mustafa

Floyd Levine as Sal Carboni

Charles Fleischer as Prisoner

Vincent Schiavelli as Carl

Brett Baxter Clark as Paradise Doorman

Kevin Costner as Frat Boy #1

Shannen Doherty as Bluebird

Michael Pataki as Courtroom Mooner

Elizabeth Carder as Dolores

Joy Michael Vogelbacher as Jacuzzi Girl

Ron Howard as Annoying Sax Player (uncredited)

Badja Djola as Cleon