Michelle Pfeiffer as Rosie

Paul Rudd as Adam

Saoirse Ronan as Izzie

Stacey Dash as Brianna

Sarah Alexander as Jeannie

Graham Norton as Taylor

Jon Lovitz as Nathan

Fred Willard as Marty

Tracey Ullman as Mother Nature

Yasmin Paige as Melanie

Rory Copus as Dylan

O-T Fagbenle as Sean

Jayden Berry-Garvey as Ike

Iddo Goldberg as Director

Noah Lee Margetts as Monty

Jonathan Ryland as Prop Guy

Phil Cornwell as Cameraman

Ray Thacker as Camera Assistant

Twink Caplan as Sissy

Olivia Colman as Hairdresser

Celia Meiras as Editor

Steve Pemberton as Censor

Simon Kunz as Intruder

Archie Panjabi as Casting Girl

Ben Bennett as Woody Wannabe

Chike Chan as Allergy Actor

John-Paul Horsley as Stuttering Actor

Mackenzie Crook as Producer

Peter Polycarpou as 2nd Producer

Doña Croll as Marty's Secretary

David Mitchell as David - Writer

Sally Kellerman as Herself

Ashley Lloyd as Zak

Troy Gentile as Fighting Boy

Cassandra Bell as Pretty Waitress

Ed Byrne as Delivery Boy

Sam Fusaro as Bouncer

Joe Montana as Very Large Guy

Victoria Chalaya as Nathan's Wife

James Harley as Parent

Jennifer Sims as Parent 2

Erin Gavin as Dancer (uncredited)

Rene Costa as Diner (uncredited)

Kya Garwood as Filming Crew (uncredited)

Melanie Martin as Sean's Wife (uncredited)

Wallace Shawn as Math Teacher (uncredited)

Henry Winkler as Self (uncredited)

Ronan Summers as Staff Writer (uncredited)

Lasco Atkins as Club Dancer (uncredited)

Jed Bernard as Bat Boy (uncredited)

Michelle Kochanski as Club Girl (uncredited)

Owen Stanley as John (uncredited)