Steve Martin as Gil Buckman

Mary Steenburgen as Karen Buckman

Dianne Wiest as Helen Buckman Lampkin Bowman

Jason Robards as Frank Buckman

Rick Moranis as Nathan Huffner

Tom Hulce as Larry Buckman

Martha Plimpton as Julie Buckman-Lampkin Higgins

Keanu Reeves as Tod Higgins

Harley Jane Kozak as Susan Buckman

Joaquin Phoenix as Garry Buckman-Lampkin

Dennis Dugan as David Brodsky

Eileen Ryan as Marilyn Buckman

Helen Shaw as Grandma

Jasen Fisher as Kevin Buckman

Paul Linke as George Bowman

Alisan Porter as Taylor Buckman

Zachary La Voy as Justin Buckman

Ivyann Schwan as Patty Huffner

Alex Burrall as Cool Buckman

Lowell Ganz as Stan

Rance Howard as Dean at College

Max Elliott Slade as Young Gil Buckman

Clint Howard as Lou

Lamont Lofton as Fotomat Clerk

Erika Rafuls as Amy

Jordan Kessler as Matt

Billy Cohen as Eddie

Isabel Cooley as Barbara Rice

Walter von Huene as Opposing Coach

Howie Dorough as Kid in Classroom (uncredited)

Greg Gerard as Doctor Lucas

Paul Keeley as Kevin Buckman - Age 21

Claudio Jacobellis as Student 1 at College

W. Bruce O'Donoghue as Umpire

Hillary Matthews as Student 2 at Collage

Sherry Ferguson as Screaming Co-ed

Todd Hallowell as Track Official

Richard Kuhlman as Young Frank Buckman

Charmin Lee as Nurse at Hospital

Bryce Dallas Howard as Redheaded Audience Girl (uncredited)