Britt Robertson as Casey Newton

George Clooney as Frank Walker

Raffey Cassidy as Athena

Hugh Laurie as David Nix

Tim McGraw as Eddie Newton

Chris Bauer as Frank's Dad

Shiloh Nelson as Young Casey Newton

Kathryn Hahn as Ursula

Keegan-Michael Key as Hugo

Thomas Robinson as Young Frank Walker

Pierce Gagnon as Nate Newton

Matthew MacCaull as Dave Clark

Judy Greer as Jenny Newton

Matthew Kevin Anderson as Bus Driver

Michael Giacchino as Small World Operator

D. Harlan Cutshall as Skyscraper Foreman

Xantha Radley as History Teacher

David Nykl as Science Teacher

Paul McGillion as English Teacher

Pearce Visser as Beefy Cop

Garry Chalk as Jail Desk Jockey

Dagan Nish as Jail Punk

Yusuf A. Ahmed as Jetpack Dexter

Alex Barima as Jetpack Buddy

Jedidiah Goodacre as Jetpack Buddy

Kate Crutchlow as Monorail Mother

Priya Rajaratnam as Young Astronaut

Parm Soor as Astronaut's Father

Leena Manro as Astronaut's Mother

Rick Pearce as Pickup Driver

Tom Butler as Police Captain

Michael Rowe as Deputy

Tim Perez as Deputy

Patrick Sabongui as Eiffel Tower Guard #1

Romuald Hivert as Eiffel Tower Guard #2

Mathieu Lardier as Pierre Clark

Fraser Corbett as Jensen

Darren Shahlavi as Tough Guard

Aidan Gemme as Young British Recruiter

Takayuki Oki as Guitar Player

Natasha Davidson as GM Plant Worker

Liliane Leilan Juma as Haitian Woman

Paul Anthony as Thick Glasses (uncredited)

Kenia Arias as DQ Patron (uncredited)

Kimberly Arklie as Hero Bus Patron (uncredited)

Nicholas Barrera as World's Fair Patron (uncredited)

Barbara Keegan as World's Fair Patron (uncredited)

Jason Bell as Dave Clark #7 (uncredited)

Wendy Bell as Guest (uncredited)

Aimee Bowen as Pedestrian (uncredited)

Chrystall Friedemann as World's Fair Lady (uncredited)

PewDiePie as PewDiePie (uncredited)

Darien Provost as Mikey (uncredited)

Jackson Tessmer as 1964 World's Fair Boy (uncredited)

Marcus Rosner as Handsome Harry (uncredited)

Julie Johnson as Harry's Girlfriend (uncredited)

Marshall Archibald as Justin (uncredited)

Clint Carleton as Pierre Clark (uncredited)

Luis Castilleja as Gentleman - 1964 World Fair (uncredited)

Ellen Marguerite Cullivan as Neighbor (uncredited)

Leslie Danielsen as DQ Patron (uncredited)

Michael Ray Davis as Lonely Man (uncredited)

Peter Dwerryhouse as Nix Six (Scientist Financier) (uncredited)

Lindsey Elizabeth as Alice (uncredited)

Amy Esterle as Greyhound Girl (uncredited)

Monique Ganderton as Dave Clark #1 (uncredited)

Glen Gordon as Donnie / Science Kid (uncredited)

Kory Grim as Dave Clark Henchman (uncredited)

Robert Peoples as Pedestrian (uncredited)

Anthony J. James as DQ Patron (uncredited)

Tomas Johansson as 1964 World's Fair Patron (uncredited)

Kenneth Kantymir as Nix Six (uncredited)

Andrew Kerr as 1964 World's Fair Attendee (uncredited)

Joshua Lagos as Neighbor (uncredited)

Tommy Lentsch as Driver (uncredited)

Laura MacKillop as Betsy (uncredited)

Grae Marino as Motorist (uncredited)

Catherine Michaud as Young Attendee (uncredited)

Jaeda Lily Miller as Young Casey (uncredited)

Lochlyn Munro as Uncle Anthony (uncredited)

Aliyah O'Brien as Functionary (uncredited)

Eddie Perez as Dave Clark #2 (uncredited)

Marc Primiani as World's Fair Patron (uncredited)

Kinley Rice as 1964 World Fair Girl (uncredited)

Kelly Riese as Woman in Car (uncredited)

Robin T. Rose as Game Warden (uncredited)

Bruce Salomon as Max / Louis (uncredited)

Ranjit Samra as Pilot (uncredited)

Manoj Sood as Economics Teacher (uncredited)