Tyler Perry as Madea / Brian / Joe

Rochelle Aytes as Lisa

Lisa Arrindell as Vanessa

Lynn Whitfield as Victoria

Blair Underwood as Carlos

Boris Kodjoe as Frankie

Keke Palmer as Nikki

Cicely Tyson as Myrtle

Maya Angelou as May

Jenifer Lewis as Milay Jenay Lori

Tangi Miller as Donna

Henry Simmons as Issac

China Anderson as Nima

Akhil Jackson as Jonathan

Alonzo Millsap as Tre

Georgia Allen as Ruby

Cassi Davis as Aunt Sarah

Leon Lamar as Grover

John Lawhorn as Uncle Pete

Afemo Omilami as Isaac Sr.

Ryan Gentles as Stripper Policeman

Mablean Ephriam as Judge Mablean Ephriam

Richard Reed as Bailiff #1

Dale Neal as Kid #1

Michelle Griffin as Carlos' Woman Friend

Cedric Pendleton as Carlos' Man Friend

Deanna Dawn as Tyrequa

Enoch King as Hykeem

Ginnie Randall as Miss Samuel

C.O.C.O. Brown as Poet / MC

Jennifer Sears as Female at Reunion

Tre Rogers as Young Man at Reunion

Shannon Eubanks as Secretary

Emmbre Perry as Man on the Bus

Jeronn C. Williams as Singer / Reverend

Dale C. Bronner as Reverend

Derrick Simmons as

Roshika West as Family Member