Dudley Moore as Emory Leeson

Daryl Hannah as Kathy Burgess

Paul Reiser as Stephen Bachman

J. T. Walsh as Drucker

Bill Smitrovich as Bruce

Alan North as Judge

David Paymer as George

Danton Stone as Saabs

Paul Bates as Robles

Dick Cusack as Mort

Doug Yasuda as Hsu

Floyd Vivino as Eddie Aris

Mercedes Ruehl as Dr. Liz Baylor

Ben Hammer as Dr. Koch

David Packer as Mark Olander

Joyce Bowden as Young Executive Anderson

Randell Haynes as Powell

James V. Albanese as Taxi Driver

Scott Kitts as Draftsman

Lorri Lindberg as Stephen's Secretary

Ann Pierce as William Holden

Faris Herbert Harton as Naked Man

Kim Clark as Very Large Man

Don Hupp as Ficus Tree Man

Pam La Testa as Heavy Woman

Bob Martana as Heavy Man

Jill Pierce as Heavy Daughter

Christine Larson-Nitzsche as Operator #1

Doris Dworsky as Operator #2

Elaine Bays as Operator #3

John Bennes as Pharmacist

Julian Bell as TV Anchor

Maggie Han as Connie Vega-Margolis

Robert K. Weiss as Outraged Movie Patron

Farryl Lovett as Girl in Booth

Sharon Frazier as Exercise Therapist

Lynda Clark as Executive #1

Mark Joy as Executive #2

Pamela D. Reid as Bahamas Receptionist

J. Michael Hunter as Eric the Orderly

Alex Barad as Boy in T.V. Department

David Muir as Continental Express Driver

Alan Haufrect as Hit and Run Victim

Ed Lillard as Senior Executive Matthews

Steve Bradford as Nervous Executive Harris

Margaret Poole Griffin as Art Therapist

Mitch Markowitz as Utility Nut

Mick McGovern as Rig Driver

Raf Nazario as Taxi Driver

Lloyd Kino as Mr. Yamashita

Robert Ito as Yamashita's Aide

John Marshall Jones as Montesque

John Terlesky as Adam Burgess

Larry King as Larry King