James Franciscus as Brent

Kim Hunter as Zira

Maurice Evans as Dr. Zaius

Charlton Heston as Taylor

Linda Harrison as Nova

Paul Richards as Mendez

Victor Buono as Fat Man

James Gregory as Ursus

David Watson as Cornelius

Jeff Corey as Caspay

Natalie Trundy as Albina

Thomas Gomez as Minister

Don Pedro Colley as Negro

Tod Andrews as Skipper

Eldon Burke as Gorilla Sgt.

Gregory Sierra as Verger

Lou Wagner as Luicius

Army Archerd as Gorilla (uncredited)

Edward Bach as Picket (uncredited)

James Bacon as Ape (uncredited)

Stan Barrett as Gorilla (uncredited)

Angelina Bauer as Chimp Protestor (uncredited)

Erlynn Mary Botelho as Ape (uncredited)

Maxine Botelho as Chimp Protester (uncredited)

Dick Bullock as Gorilla (uncredited)

Bruce Fleischer as Gorilla (uncredited)

Paul Frees as Ending Voiceover (uncredited) (voice)

Hank Robinson as Bomb Worshipper (uncredited)