Anne Shirley as Jean Johnson

Edward Ellis as Dr. John Abbott

Lee Bowman as Dick Abbott

William Henry as Howard Sykes

John Wray as Tom Johnson

Granville Bates as George Sykes

Harlan Briggs as Homer Ramsey

Frank M. Thomas as Jode Harkness

Dickie Jones as Dick Abbott (as a boy)

Dick Elliott as Hank

Carole Leete as Jean Johnson - Age 4

Gilbert Emery as Dr. Robinson

Joe De Stefani as Jorgensen

Barlowe Borland as Doctor with News of Polio Outbreak (uncredited)

Maurice Costello as Town Councilor (uncredited)

Sarah Edwards as Clerk (uncredited)

Byron Foulger as Bank Teller (uncredited)

Bud Geary as Worried Father (uncredited)

Julia Griffith as Funeral Observer (uncredited)

Charles Halton as Atty. Clyde Perkins (uncredited)

Vinton Hayworth as Huber (uncredited)

John Ince as Man at Hospital Dedication (uncredited)

Lloyd Ingraham as Funeral Observer (uncredited)

Frank Jaquet as Funeral Observer (uncredited)

Wilfred Lucas as Man at Hospital Dedication (uncredited)

Edmund Mortimer as Medical Association Board Member (uncredited)

Frank O'Connor as Man at Hospital Dedication (uncredited)

Sam Rice as Funeral Observer (uncredited)

Larry Steers as Medical Association Board Member (uncredited)

Grady Sutton as Raymond (uncredited)

Julius Tannen as Hospital Administrator (uncredited)

Lucille Ward as Gossipy Funeral Observer (uncredited)

Crane Whitley as Tough Guy Funeral Observer (uncredited)