James Stewart as Will Lockhart

Arthur Kennedy as Vic Hansbro

Donald Crisp as Alec Waggoman

Cathy O'Donnell as Barbara Waggoman

Alex Nicol as Dave Waggoman

Aline MacMahon as Kate Canaday

Wallace Ford as Charley O'Leary

Jack Elam as Chris Boldt

John War Eagle as Frank Darrah

James Millican as Tom Quigby

Gregg Barton as Fritz

Boyd Stockman as Spud Oxton

Frank De Kova as Padre

Beulah Archuletta as Woman at Indian Wedding (Uncredited)

Jack Carry as Mule Driver (uncredited)

Bill Catching as Mule Driver (uncredited)

Frank Cordell as Mule Driver (uncredited)

Kay Koury as Indian (uncredited)

Frosty Royce as Mule Driver (uncredited)

Eddy Waller as Dr. Selden (uncredited)