Rose McGowan as Courtney Shayne

Rebecca Gayheart as Julie Freeman

Julie Benz as Marcie Fox

Judy Greer as Fern Mayo

Pam Grier as Detective Vera Cruz

Carol Kane as Ms. Sherwood

Chad Christ as Zack Tartak

Ethan Erickson as Dane Sanders

Tatyana Ali as Brenda

Charlotte Ayanna as Liz Purr

Jeff Conaway as Marcie's Father

William Katt as Mr. Purr

P. J. Soles as Mrs. Purr

Marilyn Manson as The Stranger

Vylette Fagerholm as Make-Up Monger #2

The Donnas as Themselves

Alexandra Adi as Cheerleader #1

Claudine Claudio as Drama Student #2

Brian Gattas as Drama Student #1

Lisa Robin Kelly as Cheerleader #2

Sandy Martin as Nurse

Michael McLafferty as College Stud

Donna Pieroni as Cooking Teacher

Ann Russo as Gothic Girl

Rebecca Street as Mom Freeman

Rachel Winfree as English Teacher