Frank Morgan as J. Daniel 'Dan' Thompson

Mary Howard as Mary Thompson

Billie Burke as Bernice Marshall, Boardinghouse Keeper

Donald Meek as Professor Charles W. Birdo

Marjorie Main as Irma, the Cook

Connie Gilchrist as Mrs. Evelyn Diamond

Bonita Granville as Francine 'Frankie' Diamond

Dan Dailey as Ed LeMotte (as Dan Dailey Jr.)

Andrew Tombes as 'Doc' Dunbar

Walter Catlett as 'Doc' Skelby

Joseph J. Greene as Mr. Robert Emmett Ferderber, Private Detective (as Joseph J. Green)

Phil Silvers as Murdock, Side Show Barker

Irving Bacon as Carriage Driver

James Flavin as Policeman

Mayta Palmera as Little Cairo