Don Cheadle as Paul Rusesabagina

Sophie Okonedo as Tatiana Rusesabagina

Nick Nolte as Colonel Oliver

Fana Mokoena as General Bizimungu

Joaquin Phoenix as Jack Daglish

Jean Reno as Sabena Airlines President, Mr. Tillens

Desmond Dube as Dube

Ofentse Modiselle as Roger Rusesabagina

Mathabo Pieterson as Diane Rusesabagina

Hakeem Kae-Kazim as George Rutaganda

Tony Kgoroge as Gregoire

Lebo Mashile as Odette

Antonio David Lyons as Thomas Mirama

Leleti Khumalo as Fedens

Neil McCarthy as Jean Jacques

Mabutho 'Kid' Sithole as Head Chef

Jeremiah Ndlovu as Old Guard

Mosa Kaiser as Elys Rusesabagina

David O'Hara as David

Lennox Mathabathe as Peter

Mothusi Magano as Benedict

Simo Mogwaza as Hutu Captain

Cara Seymour as Pat Archer

Roberto Citran as Priest

Mduduzi Mabaso as Hutu Lieutenant

Harriet Lenabe as Alice the Waitress

Xolani Mali as Policeman

Rosie Motene as Receptionist