Harvey Keitel as Det. Rocco Klein

John Turturro as Det. Larry Mazilli

Delroy Lindo as Rodney Little

Mekhi Phifer as Ronald 'Strike' Dunham

Isaiah Washington as Victor Dunham

Keith David as André the Giant

Peewee Love as Tyrone 'Shorty' Jeeter

Regina Taylor as Iris Jeeter

Thomas Jefferson Byrd as Errol Barnes

Sticky Fingaz as Scientific

Fredro Starr as Go

Elvis Nolasco as Horace

Lawrence B. Adisa as Stan

Hassan Johnson as Skills

Frances Foster as Gloria

Michael Imperioli as Detective Jo-Jo

Lisa Arrindell as Sharon, Victor's Wife

Paul Calderon as Jesus at Hambones

Brendan Kelly as Big Chief

Mike Starr as Thumper

Graham Brown as Mr. Herman Brown

Steve White as Darryl Adams

Spike Lee as Chucky

Shawn McLean as Solo

Arthur J. Nascarella as Bartucci

Harry Lennix as Bill Walker

Bray Poor as Detective #1

Craig McNulty as Detective #2

Christopher Wynkoop as Detective #3

Paul Schulze as Detective #4

Donald Stephenson as Detective #5

John Fletcher as Medic A

J.C. MacKenzie as Medic Frank

David Evanson as Smart Mike

Norman Matlock as Reverend Paul

Isaac Flower as Charles

Leonard L. Thomas as Onion, Bar Patron

Maurice Sneed as Davis, Bartender

Calvin Hart as Guard #1

Ginny Yang as Kiki

Michael Badalucco as Cop #1

Rick Aiello as Cop #2

Scot Anthony Robinson as Earl

Richard Ziman as Moe

David Batiste as T

Mar'qus Sample as Ivan

Mar'rece Sample as Mark

Ron Brice as Dead Man Begging

Ken Garito as Louie

Anthony Nocerino as Teen #1

Brian Konowal as Teen #2

Michael McGruther as Teen #3

Carlo Vogel as Teen #4

Harvey Williams as 'Pick Me Up' Kid

Michael Cullen as Narc #1

Tim Kelleher as Narc #2

Skipp Sudduth as Narc #3

Larry Mullane as Narc Larry

Patrick Ferraro as Bike Cop #1

L.B. Williams as Bike Cop #2

Jeff Ward as Bike Cop #3

Ronda Fowler as Bomb Girl

Hal Sherman as Himself - Forensics Officer

Marc Webster as EMS Technician

James Saxenmeyer as EMS Attendant #1

Paul DuBois as EMS Attendant #2

Jordan Brown as EMS Attendant #3

Michael Marchetta as Corrections Officer #1

Joanna Gardner as Corrections Officer #2

Mark Howard as Baby Recruit #1

Michael Shepherd as Baby Recruit #2

Gerald King as Baby Recruit #3

Ronta Davis as Baby Recruit #4

Lord Kayson as T's Crewmember #1

Orran Farmer as T's Crewmember #2

Wayne Muhammed as Fruit of Islam Vendor

Martin Jaffe as Street Vendor

Freddie Velez as Pedro, Security Guard