Cary Grant as Roger Thornhill

Eva Marie Saint as Eve Kendall

James Mason as Phillip Vandamm

Jessie Royce Landis as Clara Thornhill

Leo G. Carroll as Professor

Josephine Hutchinson as Mrs. Townsend

Philip Ober as Lester Townsend

Martin Landau as Leonard

Adam Williams as Valerian

Edward Platt as Victor Larrabee

Robert Ellenstein as Licht

Les Tremayne as Auctioneer

Philip Coolidge as Dr. Cross

Patrick McVey as Sergeant Flamm

Edward Binns as Captain Junket

Ken Lynch as Charley

Nora Marlowe as Anna, the Menacing Housekeeper (uncredited)

Doreen Lang as Maggie - Thornhill's Secretary (uncredited)

John Beradino as Sergeant Emile Klinger (uncredited)

Ned Glass as Ticket Seller (uncredited)

Tol Avery as State Police Detective (uncredited)

Malcolm Atterbury as Man at Prairie Crossing (uncredited)

Maudie Prickett as Hotel Maid Elsie (uncredited)

Bess Flowers as Plaza Hotel Lounge Patron (uncredited)

Stanley Adams as Lieutenant Harding (uncredited)

Andy Albin as Farmer (uncredited)

Ernest Anderson as Porter on Twentieth Century Ltd. (uncredited)

Frank Wilcox as Herman Weltner (uncredited)

Brandon Beach as Man at Auction (uncredited)

Steve Carruthers as Man at Auction (uncredited)

Taggart Casey as Shaving Man (uncredited)

Bill Catching as Auction Attendant (uncredited)

Walter Coy as U.S. Intelligence Agency Official (uncredited)

Jimmy Cross as Taxi Driver #1 (uncredited)

Patricia Cutts as Hospital Patient (uncredited)

Jack Daly as Train Steward (uncredited)

John Damler as Police Lieutenant (uncredited)

Lawrence Dobkin as U.S. Intelligence Agency Official (uncredited)

Tommy Farrell as Eddie - Elevator Starter (uncredited)

Jesslyn Fax as Train Passenger (uncredited)

Adolph Faylauer as Bald Bidder (uncredited)

Sally Fraser as Second United Nations Receptionist (uncredited)

Paul Genge as Lieutenant Hagerman (uncredited)

James Gonzalez as Man at Auction (uncredited)

Tom Greenway as Silent State Police Detective (uncredited)

Robert Haines as Man at United Nations Building (uncredited)

Stuart Hall as Train Passenger (uncredited)

Alfred Hitchcock as Man Who Misses Bus (uncredited)

Stuart Holmes as Hotel Lounge Patron (uncredited)

Eugene Jackson as Security Guard at Auction (uncredited)

Bobby Johnson as Waiter (uncredited)

Kenner G. Kemp as Man Leaving Office Building (uncredited)

Madge Kennedy as Mrs. Finlay (uncredited)

Colin Kenny as Man at Auction (uncredited)

Carl M. Leviness as Man at United Nations Building (uncredited)

Alexander Lockwood as Judge Anson B. Flynn (uncredited)

Frank Marlowe as Taxi Driver (uncredited)

Baynes Barron as Taxi Driver #2 (uncredited)

Thomas Martin as Train Passenger (uncredited)

James McCallion as Plaza Valet (uncredited)

Maura McGiveney as Attendant (uncredited)

Carl Milletaire as Hotel Clerk (uncredited)

Hans Moebus as Man at United Nations Building (uncredited)

Howard Negley as Conductor on Twentieth Century, Ltd. (uncredited)

Monty O'Grady as Man at United Nations Building (uncredited)

Ralph Reed as Bellhop (uncredited)

John Roy as Train Passenger (uncredited)

Jeffrey Sayre as Hotel Lounge Patron / Man at Mt. Rushmore Cafeteria (uncredited)

Scott Seaton as Man at Auction (uncredited)

Harry Seymour as Victor - Captain of Waiters (uncredited)

Robert Shayne as Larry Wade (uncredited)

Jeremy Slate as Policeman at Grand Central Station (uncredited)

Olan Soule as Assistant Auctioneer (uncredited)

Helen Spring as Bidder (uncredited)

Harvey Stephens as Stockbroker (uncredited)

Harry Strang as Assistant Conductor (uncredited)

Arthur Tovey as Man at Auction (uncredited)

Dale Van Sickel as Ranger (uncredited)

Lloyd Williams as Minor Role (uncredited)

Robert B. Williams as Patrolman Waggoner (uncredited)

Paula Winslowe as Woman at Auction (uncredited)

Wilson Wood as Photographer at United Nations (uncredited)

Carleton Young as Fanning Nelson (uncredited)

Dick Johnstone as Courtroom Spectator (uncredited)

Bert Stevens as Man at United Nations Building (uncredited)

Cosmo Sardo as Worker (uncredited)

Don Anderson as Worker (uncredited)

Alphonso DuBois as Man at United Nations Building (uncredited)

Len Hendry as Police Lieutenant (uncredited)

Anne Anderson as Woman (uncredited)

Rama Bai as Woman at United Nations Building (uncredited)

Finn Zirzow as Worker (uncredited)

Roger C. Carmel as Tall Man in Crowd (uncredited)

Donna Douglas as Woman on Sidewalk (uncredited)

Caryl Lincoln as Auction Guest (uncredited)