Burt Lancaster as Marshal Wyatt Earp

Kirk Douglas as Dr. John 'Doc' Holliday

Jo Van Fleet as Kate Fisher

Rhonda Fleming as Laura Denbow

John Ireland as Johnny Ringo

Lyle Bettger as Ike Clanton

Frank Faylen as Sheriff Cotton Wilson

Earl Holliman as Deputy Sheriff Charles 'Charlie' Bassett

Ted de Corsia as Shanghai Pierce

Dennis Hopper as Billy Clanton

Whit Bissell as 'Tombstone Epitaph' Editor John P. Clum

George Mathews as Griffin Saloonkeeper John Shanssey

John Hudson as Virgil Earp

DeForest Kelley as Morgan Earp

Martin Milner as James 'Jimmy' Earp

Kenneth Tobey as Bat Masterson

Lee Van Cleef as Ed Bailey

Joan Camden as Betty Earp

Olive Carey as Mrs. Clanton

Brian G. Hutton as Rick

Nelson Leigh as Mayor Kelly

Jack Elam as Tom McLowery

Don Castle as Drunk Cowboy in Longbranch Saloon

Franklyn Farnum as Barfly (uncredited)

Charles Herbert as Tommy Earp (uncredited)

Kenner G. Kemp as Croupier (uncredited)

Colin Kenny as Barfly (uncredited)

Bert Stevens as Party Guest (uncredited)

Arthur Tovey as Barfly (uncredited)

Leslie Sketchley as Barfly (uncredited)

John Benson as Stage Driver (uncredited)

Frank Hagney as Bartender (uncredited)

Richard Reeves as Pierce's Foreman (uncredited)

Charles Fogel as Barfly (uncredited)

Raoul Freeman as Party Guest (uncredited)

Stuart Hall as Party Guest (uncredited)

Dorothy Abbott as Girl (uncredited)

John Alban as Barfly (uncredited)

William Bailey as Party Guest (uncredited)

Herman Belmonte as Townsman (uncredited)

Danny Borzage as Accordionist (uncredited)

Rudy Bowman as Party Guest (uncredited)

Paul Bradley as Joe (uncredited)

Nora Bush as Party Guest (uncredited)

Frank Carter as Hotel Clerk (uncredited)

Miguel Contreras as Townsman (uncredited)

Roger Creed as Deputy / Killer / Townsman (uncredited)

James Davies as Card Player (uncredited)

Harry Denny as Party Guest (uncredited)

Art Felix as Townsman (uncredited)

Joseph Forte as Tombstone Card Player (uncredited)

Paul Gary as Killer (uncredited)

Paul Gustine as Townsman (uncredited)

Robert Haines as Barfly (uncredited)

Len Hendry as Cowboy (uncredited)

Tex Holden as Cowboy (uncredited)

Stuart Holmes as Barfly (uncredited)

Edward Ingram as Deputy (uncredited)

Anthony Jochim as Old Man (uncredited)

Leroy Johnson as Cowboy (uncredited)

Dave Kashner as Cowboy (uncredited)

Jack Kenny as Barfly (uncredited)

Ann Kunde as Party Guest (uncredited)

Ethan Laidlaw as Bartender (uncredited)

Morgan Lane as Killer (uncredited)

Gregg Martell as Cowboy (uncredited)

John Maxwell as Merchant at Dance (uncredited)

William Meigs as Wayne (uncredited)

Harry Mendoza as Frank Loving - Dealer (uncredited)

Walter Merrill as Mario - Dodge City Barber (uncredited)

Dennis Moore as Cowboy (uncredited)

Sol Murgi as Barfly (uncredited)

Max Power as Card Player (uncredited)

Ford Raymond as Barfly (uncredited)

Lee Roberts as Finn Clanton (uncredited)

Bing Russell as Harry - Griffin Bartender (uncredited)

Rube Schaffer as Barfly (uncredited)

Bernard Sell as Barfly (uncredited)

Court Shepard as Card Player (uncredited)

Mickey Simpson as Frank McLowery (uncredited)

Glenn Strange as Pierce Henchman in Saloon (uncredited)

Robert Swan as Shaugnessy Man (uncredited)

Slim Talbot as Barfly (uncredited)

Al Thompson as Waiter (uncredited)

Blaine Turner as Bartender (uncredited)

Dorothy Vernon as Party Guest (uncredited)

Henry Wills as Alby (uncredited)

Trude Wyler as Party Guest (uncredited)