Karra Elejalde as Mortadelo / Tía Fulgencia (voice)

Janfri Topera as Filemón (voice)

Gabriel Chame Buendía as Jimmy el Cachondo (voice)

Ramón Langa as Filemón en sueños (voice)

Mariano Venancio as El Súper (voice)

Víctor Monigote as Tronchamulas reversizado (voice)

José Alias as Tronchamulas (voice)

Emilio Gavira as Rompetechos (voice)

Enrique Villén as El Profesor Bacterio (voice)

Berta Ojea as Ofelia (voice)

Athenea Mata as Señorita Irma (voice)

Chani Martín as Mari (voice)

Manuel Tallafé as Trini (voice)

Javier Laorden as Guardia / Niño 2 (voice)

Rocío Calvo as Vecina Filemón / Niño 3 (voice)

Karlos Arguiñano as Cocinero TV (voice)

Javier Fesser as Instalador caja fuerte / Voz sobre el periódico (voice)

Iesus Salamanca as Ciego / Yoyolanda reversizada (voice)

Isabel Nuñez as Yoyolanda / Reportera noticiaria TV (voice)

Claudia Fesser as Bicho 1 / Pingüino (voice)